Saturday, August 3, 2013

Prognostic factors in choriocarcinoma


• Age / Parity - 

  worse if > 39 years and > Para 4

• Antecedent pregnancy - 

  worse after full term pregnancy / spontaneous miscarriage, better after known molar pregnancy

• Interval between pregnancy and chemotherapy - 

  better if < 4 months, worse if > 12 months

• Blood group - 

  better in blood groups O and A, worse in blood groups B and AB

• HCG levels - 

  better if < 100,000IU, worse if > 100,000IU

• Presence of metastases - 

  better if none, worse if brain, better if 1-3 metastases, worse if >3 metastases

• Largest tumour mass - 

  better if <3cm, worse if >5cm

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