• Hypoglycaemic therapy should be considered if diet and exercise fail
to maintain blood glucose targets during a period of 1–2 weeks.
• Hypoglycaemic therapy should be considered if ultrasound investigation
suggests incipient fetal macrosomia (abdominal circumference above the
70th percentile) at diagnosis.
• Hypoglycaemic therapy may include regular insulin, rapid-acting
insulin analogues [aspart and lispro] and/or oral hypoglycaemic agents
[metformin and glibenclamide].
Treatment should be tailored to the
glycaemic profile of, and acceptability to, the individual woman.
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