Infections in SLE :
- Patients with SLE may be functionally asplenic and at risk from encapsulated bacterial infections like meningococcemia.
- Immunosuppred patients are at increased risk of sepsis
- Infection can mimic a lupus flare
- ESR and CRP may be raised. CRP changes more acutely, and the ESR lags behind disease changes.
- Measurement of complement may be useful as C3 and C4 levels are reduced in patients with active SLE due to consumption by immune complex–induced inflammation.
- Patients with SLE may be functionally asplenic and at risk from encapsulated bacterial infections like meningococcemia.
- Immunosuppred patients are at increased risk of sepsis
- Infection can mimic a lupus flare
- ESR and CRP may be raised. CRP changes more acutely, and the ESR lags behind disease changes.
- Measurement of complement may be useful as C3 and C4 levels are reduced in patients with active SLE due to consumption by immune complex–induced inflammation.
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