Causes of azoospermia - 2

2) Primary testicular failure (nonobstructive azoospermia): 

The diagnosis is based on reduction in testicular size and elevation of serum FSH levels. 

It is the most common cause of male infertility due to oligozoospermia. 

May be due to:

• Cryptorchidism
• Torsion
• Trauma
• Orchitis
• Chromosome disorders (Klinefelter’s syndrome, Y-chromosome microdeletions)
• Systemic disease
• Radiotherapy or chemotherapy
• Idiopathic (66%)

There is no effective treatment. 

Men undergoing treatments that cause infertility should be offered the opportunity to cryopreserve semen.