Tuesday, August 13, 2013

Anovulation in hyperprolactinemia

Hyperprolactinemic anovulation -

- 5-10% anovulation

- Anovulatory because hyperprolactinemia inhibits gonadotropin and therefore estrogen secretion. 

- Most have oligomenorrhea or amenorrhea. 

- Their serum gonadotropin concentrations are usually normal or decreased. 

- Hyperprolactinemia should always be confirmed by several measurements of serum prolactin. 


- An MRI of the head should be done in whom the cause is not obvious (eg, neuroleptic drug therapy, primary hypothyroidism).

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