• Complete moles have a 46XX karyotype - caused by a single sperm
fertilising an anucleate oocyte then duplicating its genetic material
• Secrete large quantities of HCG
• Characterised by hydropic avascular villi with a snow-storm appearance on ultrasound scan
• The alpha subunit of HCG is identical to the alpha subunit of TSH and high levels of HCG may cause symptomatic hyperthyroidism
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