Antiphospholipid antibody syndrome

• Primary antiphospholipid syndrome is the association between anti-phospholipid antibodies and adverse pregnancy outcome or vascular thrombosis

• Adverse pregnancy outcomes include :

- 3 or more consecutive miscarriages before 10 weeks, 
- one or more morphologically normal fetal death after 10 weeks or 
- one or more pre-term deliveries before 34 weeks due to pre-eclampsia or IUGR