Saturday, July 13, 2013

Oxytocin

Oxytocin

Why neonatal jaundice may occur after oxytocin therapy ?

- The vasopressin-like action of oxytocin causes osmotic swelling of erythrocytes leading to decreased deformability and hence more rapid destruction with resultant hyperbilirubinaemia in the neonate.

This can be minimised by administering oxytocin in sodium-free iv fluids.

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