- Acute administration of more than 1.5 times of patient's blood volume
OR
Replacement of 10 units of blood in 24 hours
OR
replacement of the patient's total blood volume within 24 hours
- What are the complications ?
1.Thrombocytopenia- dilutional
2. Coagulopathy - due to depleted clotting factors
3. Acid-base imbalance
4. Hypocalcemia - due to formation of complexes of citrate in the blood with serum calcium
5. Hyperkalemia - due to release of high potassium in stored blood cells
6. TRALI - transfusion related acute lung injury
- Iron overload does not occur.
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