Sunday, July 14, 2013

G6PD deficiency inheritance

- X-linked recessive



A) If the father is unaffected (healthy) and the mother is a carrier (no clinical symptoms):
  • One daughter out of two will be a carrier
  • One son out of two will be G6PD deficient
B) If the father is G6PD deficient and the mother is unaffected:
  • All daughters will be carriers
  • All sons will be unaffected
C) If the father is G6PD deficient and the mother is a carrier:
  • One daughter out of two will be G6PD deficient
  • One daughter out of two will be a carrier
  • One son out of two will be G6PD deficient
  • One son out of two will be unaffected
D) If the father is unaffected and the mother is G6PD deficient:
  • All daughters will be carriers
  • All sons will be G6PD deficient
E) If both father and mother are G6PD deficient:
  • All daughters will be G6PD deficient
  • All sons will be G6PD deficient

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